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Summary: Researchers say a new compound simultaneously blocks two sought after pain targets.
New drug blocks two sought-after pain targets.
A research team at Duke University has discovered a potential new class of small-molecule drugs that simultaneously block two sought-after targets in the treatment of pain.
These proof-of-concept experiments, published June 1 in Scientific Reports, could lead to the development of a new drug to treat conditions including skin irritation and itching, headaches, jaw pain, and abdominal pain stemming from the pancreas and colon.
More than 100 million people suffer from chronic pain in the United States, according to a report from the Institute of Medicine, and new medicines are badly needed.
“We are very pleased with what is a first chapter in a highly promising story,” said Wolfgang Liedtke, M.D., Ph.D., a professor of neurology, anesthesiology and neurobiology at Duke University School of Medicine, who treats patients with head and face pain and other sensory disorders. “We hope to be able to develop these compounds for clinical use in humans or animals.”/.../