Discovering the Full Spectrum of Cardiovascular Disease: Minority Health Summit 2003: Report of the Obesity, Metabolic Syndrome, and Hypertension Writing Group -- Smith et al. 111 (10): e134 -- Circulation
This article provides an overview of our current understanding
of the epidemiology of obesity, the metabolic
syndrome, and hypertension among racial/ethnic groups.
Three presentations made at the conference by the present
writing group are summarized and updated with other information
on ethnic groups, and recommendations developed by
the writing group for programs, public policy, and research
are put forward.
Tuesday, March 15, 2005
Minority Health Summit 2003: Report of the Outcomes Writing Group
Discovering the Full Spectrum of Cardiovascular Disease: Minority Health Summit 2003: Report of the Outcomes Writing Group -- Benjamin et al. 111 (10): e124 -- Circulation
Despite the steady decline in cardiovascular disease
(CVD) mortality during the past 30 years,1 CVD remains
the No. 1 killer of adults across all racial/ethnic groups
in the United States.2 Observational studies have been central
to understanding the epidemiology of CVD, including its
incidence, prevalence, predictors, and prognosis. Until recently,
the majority of epidemiological studies have been
based predominantly, or even exclusively, on middle-class,
white, non-Hispanic cohorts. Hence, the generalizability of
the findings to all populations has been uncertain. The lack of
information on the epidemiology of CVD in racial/ethnic
minority groups and people of lower socioeconomic status
(SES) is particularly problematic in light of data that underscore
the undue burden of CVD and its risk factors in
racial/ethnic minorities and poor people.3
Despite the steady decline in cardiovascular disease
(CVD) mortality during the past 30 years,1 CVD remains
the No. 1 killer of adults across all racial/ethnic groups
in the United States.2 Observational studies have been central
to understanding the epidemiology of CVD, including its
incidence, prevalence, predictors, and prognosis. Until recently,
the majority of epidemiological studies have been
based predominantly, or even exclusively, on middle-class,
white, non-Hispanic cohorts. Hence, the generalizability of
the findings to all populations has been uncertain. The lack of
information on the epidemiology of CVD in racial/ethnic
minority groups and people of lower socioeconomic status
(SES) is particularly problematic in light of data that underscore
the undue burden of CVD and its risk factors in
racial/ethnic minorities and poor people.3
Discovering the Full Spectrum of Cardiovascular Disease: Minority Health Summit 2003: Report of the Basic Science Writing Group
Discovering the Full Spectrum of Cardiovascular Disease: Minority Health Summit 2003: Report of the Basic Science Writing Group -- Benjamin et al. 111 (10): e120 -- Circulation
Despite considerable overall improvement in the clinical
prevalence and outcome of cardiovascular disease in the
US population during the past 50 years, striking disparities in
disease burden plague specific racial/ethnic subgroups. Black
patients with cardiovascular disease (CVD) in particular have
increased morbidity and mortality as compared with white
patients. For example, a black man between 45 and 65 years
old is 4 times more likely to have a stroke than his white
counterpart. Even when accounting for access to high-quality
health care, ethnic minorities bear a higher burden of obesity,
type 2 diabetes mellitus, and hypertension as compared with
whites. The mechanisms for these disparities remain incompletely
understood but likely include a combination of genetic,
environmental, and socioeconomic factors. If recent
advances in basic science are to be exploited to reduce
disparities in cardiovascular health care, then the emerging
disciplines in human genetics, biological sciences, and molecular
medicine are likely to afford us unprecedented opportunities
for deciphering the complex mechanisms involving
race/ethnicity, genetic differentiation, allele frequency disparities,
and gene– environment interactions.
Despite considerable overall improvement in the clinical
prevalence and outcome of cardiovascular disease in the
US population during the past 50 years, striking disparities in
disease burden plague specific racial/ethnic subgroups. Black
patients with cardiovascular disease (CVD) in particular have
increased morbidity and mortality as compared with white
patients. For example, a black man between 45 and 65 years
old is 4 times more likely to have a stroke than his white
counterpart. Even when accounting for access to high-quality
health care, ethnic minorities bear a higher burden of obesity,
type 2 diabetes mellitus, and hypertension as compared with
whites. The mechanisms for these disparities remain incompletely
understood but likely include a combination of genetic,
environmental, and socioeconomic factors. If recent
advances in basic science are to be exploited to reduce
disparities in cardiovascular health care, then the emerging
disciplines in human genetics, biological sciences, and molecular
medicine are likely to afford us unprecedented opportunities
for deciphering the complex mechanisms involving
race/ethnicity, genetic differentiation, allele frequency disparities,
and gene– environment interactions.
Clinical Trial Registration: A Statement From the International Committee of Medical Journal Editors -- De Angelis et al. 111 (10): 1337 -- Circulation
Clinical Trial Registration: A Statement From the International Committee of Medical Journal Editors -- De Angelis et al. 111 (10): 1337 -- Circulation
Altruism and trust lie at the heart of research on human
subjects. Altruistic individuals volunteer for research
because they trust that their participation will contribute to
improved health for others and that researchers will minimize
risks to participants. In return for the altruism and trust that
make clinical research possible, the research enterprise has an
obligation to conduct research ethically and to report it
honestly. Honest reporting begins with revealing the existence
of all clinical studies, even those that reflect unfavorably
on a research sponsor’s product.
Altruism and trust lie at the heart of research on human
subjects. Altruistic individuals volunteer for research
because they trust that their participation will contribute to
improved health for others and that researchers will minimize
risks to participants. In return for the altruism and trust that
make clinical research possible, the research enterprise has an
obligation to conduct research ethically and to report it
honestly. Honest reporting begins with revealing the existence
of all clinical studies, even those that reflect unfavorably
on a research sponsor’s product.
Eliminating Disparities in Cardiovascular Health
Six Strategic Imperatives and a Framework for Action
George A. Mensah, MD
Disparities in cardiovascular health are among the most serious public health problems in the United States today. Despite the remarkable declines in cardiovascular mortality observed nationally over the last 3 decades, many population subgroups defined by race, ethnicity, gender, socioeconomic status, educational level, or geography show striking, and often widening, disparities in cardiovascular health. The pervasive nature of these disparities and compelling evidence of the adverse impact they have on clinical outcomes and quality of life have been well documented. The elimination of these disparities is 1 of the 2 overarching goals of the Healthy People 2010 national public health agenda; however, few publications provide guidance on what actions to take. In this review, 6 strategic imperatives within a framework for action are presented. Other key elements of the framework include 10 focal areas and 6 major settings within which the framework calls for accelerated interventions to eliminate disparities in cardiovascular health. Success in this endeavor will require innovative and comprehensive interventions built on a foundation of sound clinical and public health science. Strategic partnerships with communities, community-based organizations, state and local governments, and public and private partners from both health and nonhealth sectors are essential. Additionally, investment in local-level disparities surveillance, community-based participatory research, and development of a diverse clinical and public health workforce will be invaluable.
George A. Mensah, MD
Disparities in cardiovascular health are among the most serious public health problems in the United States today. Despite the remarkable declines in cardiovascular mortality observed nationally over the last 3 decades, many population subgroups defined by race, ethnicity, gender, socioeconomic status, educational level, or geography show striking, and often widening, disparities in cardiovascular health. The pervasive nature of these disparities and compelling evidence of the adverse impact they have on clinical outcomes and quality of life have been well documented. The elimination of these disparities is 1 of the 2 overarching goals of the Healthy People 2010 national public health agenda; however, few publications provide guidance on what actions to take. In this review, 6 strategic imperatives within a framework for action are presented. Other key elements of the framework include 10 focal areas and 6 major settings within which the framework calls for accelerated interventions to eliminate disparities in cardiovascular health. Success in this endeavor will require innovative and comprehensive interventions built on a foundation of sound clinical and public health science. Strategic partnerships with communities, community-based organizations, state and local governments, and public and private partners from both health and nonhealth sectors are essential. Additionally, investment in local-level disparities surveillance, community-based participatory research, and development of a diverse clinical and public health workforce will be invaluable.
Ethnic Differences in Coronary Calcification: The Multi-Ethnic Study of Atherosclerosis (MESA)
Ethnic Differences in Coronary Calcification: The Multi-Ethnic Study of Atherosclerosis (MESA) -- Bild et al. 111 (10): 1313 -- Circulation:
"Background: There is substantial evidence that coronary calcification, a marker for the presence and quantity of coronary atherosclerosis, is higher in US whites than blacks; however, there have been no large population-based studies comparing coronary calcification among US ethnic groups.
Methods and Results: Using computed tomography, we measured coronary calcification in 6814 white, black, Hispanic, and Chinese men and women aged 45 to 84 years with no clinical cardiovascular disease who participated in the Multi-Ethnic Study of Atherosclerosis (MESA). The prevalence of coronary calcification (Agatston score >0) in these 4 ethnic groups was 70.4%, 52.1%, 56.5%, and 59.2%, respectively, in men (P<0.001) and 44.6%, 36.5%, 34.9%, and 41.9%, respectively, (P<0.001) in women. After adjustment for age, education, lipids, body mass index, smoking, diabetes, hypertension, treatment for hypercholesterolemia, gender, and scanning center, compared with whites, the relative risks for having coronary calcification were 0.78 (95% CI 0.74 to 0.82) in blacks, 0.85 (95% CI 0.79 to 0.91) in Hispanics, and 0.92 (95% CI 0.85 to 0.99) in Chinese. After similar adjustments, the amount of coronary calcification among those with an Agatston score >0 was greatest among whites, followed by Chinese (77% that of whites; 95% CI 62% to 96%), Hispanics (74%; 95% CI 61% to 90%), and blacks (69%; 95% CI 59% to 80%).
Conclusions: We observed ethnic differences in the presence and quantity of coronary calcification that were not explained by coronary risk factors. Identification of the mechan"
"Background: There is substantial evidence that coronary calcification, a marker for the presence and quantity of coronary atherosclerosis, is higher in US whites than blacks; however, there have been no large population-based studies comparing coronary calcification among US ethnic groups.
Methods and Results: Using computed tomography, we measured coronary calcification in 6814 white, black, Hispanic, and Chinese men and women aged 45 to 84 years with no clinical cardiovascular disease who participated in the Multi-Ethnic Study of Atherosclerosis (MESA). The prevalence of coronary calcification (Agatston score >0) in these 4 ethnic groups was 70.4%, 52.1%, 56.5%, and 59.2%, respectively, in men (P<0.001) and 44.6%, 36.5%, 34.9%, and 41.9%, respectively, (P<0.001) in women. After adjustment for age, education, lipids, body mass index, smoking, diabetes, hypertension, treatment for hypercholesterolemia, gender, and scanning center, compared with whites, the relative risks for having coronary calcification were 0.78 (95% CI 0.74 to 0.82) in blacks, 0.85 (95% CI 0.79 to 0.91) in Hispanics, and 0.92 (95% CI 0.85 to 0.99) in Chinese. After similar adjustments, the amount of coronary calcification among those with an Agatston score >0 was greatest among whites, followed by Chinese (77% that of whites; 95% CI 62% to 96%), Hispanics (74%; 95% CI 61% to 90%), and blacks (69%; 95% CI 59% to 80%).
Conclusions: We observed ethnic differences in the presence and quantity of coronary calcification that were not explained by coronary risk factors. Identification of the mechan"
Ischemic Stroke Subtype Incidence Among Whites, Blacks, and Hispanics: The Northern Manhattan Study
Ischemic Stroke Subtype Incidence Among Whites, Blacks, and Hispanics: The Northern Manhattan Study -- White et al. 111 (10): 1327 -- Circulation:
"Background: Stroke incidence is greater in blacks than in whites; data on Hispanics are limited. Comparing subtype-specific ischemic stroke incidence rates may help to explain race-ethnic differences in stroke risk. The aim of this population-based study was to determine ischemic stroke subtype incidence rates for whites, blacks, and Hispanics living in one community.
Methods and Results: A comprehensive stroke surveillance system incorporating multiple overlapping strategies was used to identify all cases of first ischemic stroke occurring between July 1, 1993, and June 30, 1997, in northern Manhattan. Ischemic stroke subtypes were determined according to a modified NINDS scheme, and age-adjusted, race-specific incidence rates calculated. The annual age-adjusted incidence of first ischemic stroke per 100 000 was 88 (95% CI, 75 to 101) in whites, 149 (95% CI, 132 to 165) in Hispanics, and 191 (95% CI, 160 to 221) in blacks. Among blacks compared with whites, the relative rate of intracranial atherosclerotic stroke was 5.85 (95% CI, 1.82 to 18.73); extracranial atherosclerotic stroke, 3.18 (95% CI, 1.42 to 7.13); lacunar stroke, 3.09 (95% CI, 1.86 to 5.11); and cardioembolic stroke, 1.58 (95% CI, 0.99 to 2.52). Among Hispanics compared with whites, the relative rate of intracranial atherosclerotic stroke was 5.00 (95% CI, 1.69 to 14.76); extracranial atherosclerotic stroke, 1.71 (95% CI, 0.80 to 3.63); lacunar stroke, 2.32 (95% CI, 1.48 to 3.63); and cardioembolic stroke, 1.42 (95% CI, 0.97 to 2.09).
Conclusions: The high ischemic stroke incidence among blacks and Hispanics compared with"
"Background: Stroke incidence is greater in blacks than in whites; data on Hispanics are limited. Comparing subtype-specific ischemic stroke incidence rates may help to explain race-ethnic differences in stroke risk. The aim of this population-based study was to determine ischemic stroke subtype incidence rates for whites, blacks, and Hispanics living in one community.
Methods and Results: A comprehensive stroke surveillance system incorporating multiple overlapping strategies was used to identify all cases of first ischemic stroke occurring between July 1, 1993, and June 30, 1997, in northern Manhattan. Ischemic stroke subtypes were determined according to a modified NINDS scheme, and age-adjusted, race-specific incidence rates calculated. The annual age-adjusted incidence of first ischemic stroke per 100 000 was 88 (95% CI, 75 to 101) in whites, 149 (95% CI, 132 to 165) in Hispanics, and 191 (95% CI, 160 to 221) in blacks. Among blacks compared with whites, the relative rate of intracranial atherosclerotic stroke was 5.85 (95% CI, 1.82 to 18.73); extracranial atherosclerotic stroke, 3.18 (95% CI, 1.42 to 7.13); lacunar stroke, 3.09 (95% CI, 1.86 to 5.11); and cardioembolic stroke, 1.58 (95% CI, 0.99 to 2.52). Among Hispanics compared with whites, the relative rate of intracranial atherosclerotic stroke was 5.00 (95% CI, 1.69 to 14.76); extracranial atherosclerotic stroke, 1.71 (95% CI, 0.80 to 3.63); lacunar stroke, 2.32 (95% CI, 1.48 to 3.63); and cardioembolic stroke, 1.42 (95% CI, 0.97 to 2.09).
Conclusions: The high ischemic stroke incidence among blacks and Hispanics compared with"
US-National Survey of Stroke Risk Awareness Among Women
American Heart Association and American Stroke Association National Survey of Stroke Risk Awareness Among Women -- Ferris et al. 111 (10): 1321 -- Circulation
Conclusions— Results of this national survey document that awareness and knowledge about stroke is suboptimal among women, especially among racial/ethnic minorities, who are at highest risk. These data support the need for targeted educational programs about stroke risk and symptoms and underscore the importance of public health programs to improve awareness of stroke among women.
Conclusions— Results of this national survey document that awareness and knowledge about stroke is suboptimal among women, especially among racial/ethnic minorities, who are at highest risk. These data support the need for targeted educational programs about stroke risk and symptoms and underscore the importance of public health programs to improve awareness of stroke among women.
Monday, March 14, 2005
The New York Times > Health > Tracking the Uncertain Science of Growing Heart Cells
The New York Times > Health > Tracking the Uncertain Science of Growing Heart Cells
Muito interessante...
As motivações dos cientistas e dos médicos são diferentes "indeed"... inclusiva as de ordem $$$$... onde e para quem vai o dinheiro da inovação, se para os laboratórios ou para os médicos que realizam o procedimento (transplante de medula), também é um ponto em disputa aqui?
Acho que eu torço para o transplante de medula.
Maria Inês
n April 2001, researchers from the New York Medical College and the National Institutes of Health announced electrifying news for heart surgeons and their patients: stem cells from bone marrow, injected into the damaged hearts of mice, had morphed into the special cardiac muscle cells that the body cannot replace after a heart attack.
The researchers held out the hope that the procedure could be applied to people, too. The findings underlined a basic premise of stem cell therapy, that it will work before the cells and their elaborate control systems are fully understood - just put stem cells in the right place in the body, and they will do the rest.
But four years later, the treatment has yet to demonstrate whether it will fulfill its promise. And it has touched off a sharp difference of views among clinical doctors as to whether the therapy is ready to be taken to people.
Muito interessante...
As motivações dos cientistas e dos médicos são diferentes "indeed"... inclusiva as de ordem $$$$... onde e para quem vai o dinheiro da inovação, se para os laboratórios ou para os médicos que realizam o procedimento (transplante de medula), também é um ponto em disputa aqui?
Acho que eu torço para o transplante de medula.
Maria Inês
n April 2001, researchers from the New York Medical College and the National Institutes of Health announced electrifying news for heart surgeons and their patients: stem cells from bone marrow, injected into the damaged hearts of mice, had morphed into the special cardiac muscle cells that the body cannot replace after a heart attack.
The researchers held out the hope that the procedure could be applied to people, too. The findings underlined a basic premise of stem cell therapy, that it will work before the cells and their elaborate control systems are fully understood - just put stem cells in the right place in the body, and they will do the rest.
But four years later, the treatment has yet to demonstrate whether it will fulfill its promise. And it has touched off a sharp difference of views among clinical doctors as to whether the therapy is ready to be taken to people.
Sunday, March 13, 2005
PSYCHOCARDIOLOGY: THE INTERTWINNING OF HEART AND MIND
Dr. Schvinger, Amaryllis
PsycoCardiology is a field of Clinical Psychology . Clinical Psychology had been from its beginning a part of Mental Health research and practice, but nowadays it became enrolled in the wider sphere of the Health Sciences.
From this point of reference, our view of PsychoCardiology intends to go further and affirm a radical rupture with the Cartesian epistemological model which has dualism as its core – ground of modern science – and is present in the distinction between the material (body) and the imaterial (mind or spirit) of the human being constitution. PsychoCardiology has its philosophical ground mainly in Edmund Husserl’s notion of the lived body (Leib), later developed by the French philosopher Maurice Merleau-Ponty and, the North American psychiatrist Drew Leder.
Scientific researches developed around the Body/Mind unity and interelationships, and specifically around the relations of psychological processes with cardiovascular diseases give the scientific support to the PsychoCardiology proposal.
The present work is supplemented by data from a phenomenological research conducted by the author at the Instituto Nacional de Cardiologia Laranjeiras, in Rio de Janeiro, Brazil. Clinical interviews were made with 53 inpatients that either were submitted to revascularization surgery ,1 to 8 days before the interview, or were going to be submitted to the surgery on the following 1 to 20 days after the interview.
Results point to two kinds of conexions between physical and mental or psychological processes:
1. By simultaneity: refers to conexions presented by experimental studies that search for causal relations among psychosocial factors and cardiac pathology, e.g. the Type A Behavior Pattern as an independent risk factor to MI;
2. By repercussion: refers to the acknowledgement, via phenomenological-hermeneutical reasoning, that what is experienced in the body affects the mind and vice-versa. “Psychological reactions to heart disease can be more astonishing and dramatic than those of the cardiovascular system itself” (Cassem & Hackett, 1977).
Existence, a heideggerian expression, best conveys the body/mind unity and says even more: this unity exists in intrinsic relation with the people and the world around.
Dr. Schvinger, Amaryllis
International Affiliation: American Psychological Association
Address: Estrada do Mataporcos, 2101
Corrêas Petrópolis, RJ Brazil
Postcode: 25730-070
Phone: (5521) 2521 7840 Fax: (5521)2521 7840
Email: aletheia@serraon.com.br
PsycoCardiology is a field of Clinical Psychology . Clinical Psychology had been from its beginning a part of Mental Health research and practice, but nowadays it became enrolled in the wider sphere of the Health Sciences.
From this point of reference, our view of PsychoCardiology intends to go further and affirm a radical rupture with the Cartesian epistemological model which has dualism as its core – ground of modern science – and is present in the distinction between the material (body) and the imaterial (mind or spirit) of the human being constitution. PsychoCardiology has its philosophical ground mainly in Edmund Husserl’s notion of the lived body (Leib), later developed by the French philosopher Maurice Merleau-Ponty and, the North American psychiatrist Drew Leder.
Scientific researches developed around the Body/Mind unity and interelationships, and specifically around the relations of psychological processes with cardiovascular diseases give the scientific support to the PsychoCardiology proposal.
The present work is supplemented by data from a phenomenological research conducted by the author at the Instituto Nacional de Cardiologia Laranjeiras, in Rio de Janeiro, Brazil. Clinical interviews were made with 53 inpatients that either were submitted to revascularization surgery ,1 to 8 days before the interview, or were going to be submitted to the surgery on the following 1 to 20 days after the interview.
Results point to two kinds of conexions between physical and mental or psychological processes:
1. By simultaneity: refers to conexions presented by experimental studies that search for causal relations among psychosocial factors and cardiac pathology, e.g. the Type A Behavior Pattern as an independent risk factor to MI;
2. By repercussion: refers to the acknowledgement, via phenomenological-hermeneutical reasoning, that what is experienced in the body affects the mind and vice-versa. “Psychological reactions to heart disease can be more astonishing and dramatic than those of the cardiovascular system itself” (Cassem & Hackett, 1977).
Existence, a heideggerian expression, best conveys the body/mind unity and says even more: this unity exists in intrinsic relation with the people and the world around.
Dr. Schvinger, Amaryllis
International Affiliation: American Psychological Association
Address: Estrada do Mataporcos, 2101
Corrêas Petrópolis, RJ Brazil
Postcode: 25730-070
Phone: (5521) 2521 7840 Fax: (5521)2521 7840
Email: aletheia@serraon.com.br
Saturday, March 12, 2005
Warning signs often occur hours or days before a stroke -- Mayor 330 (7491): 556 -- BMJ
Warning signs often occur hours or days before a stroke -- Mayor 330 (7491): 556 -- BMJ
Nearly one in eight patients who have an ischaemic stroke have a transient ischaemic attack (TIA) at some point in the previous seven days, according to a study published this week, indicating the need to treat TIA as a medical emergency to improve the prevention of subsequent stroke.
Nearly one in eight patients who have an ischaemic stroke have a transient ischaemic attack (TIA) at some point in the previous seven days, according to a study published this week, indicating the need to treat TIA as a medical emergency to improve the prevention of subsequent stroke.
The pre-eclampsia community guideline (PRECOG): how to screen for and detect onset of pre-eclampsia in the community -- Milne et al. 330 (7491): 576 -- BMJ
The pre-eclampsia community guideline (PRECOG): how to screen for and detect onset of pre-eclampsia in the community -- Milne et al. 330 (7491): 576 -- BMJ
Many maternal and fetal deaths from pre-eclampsia are associated with substandard care
Poor management includes failure to assess or act on risk at booking or to act on signs and symptoms after 20 weeks' gestation
Our community guideline provides an evidence based risk assessment, a list of factors suitable for early referral, and a two tiered schedule of assessment and step-up referral for signs and symptoms of pre-eclampsia
This is a practical extension of NICE's antenatal guideline
Many maternal and fetal deaths from pre-eclampsia are associated with substandard care
Poor management includes failure to assess or act on risk at booking or to act on signs and symptoms after 20 weeks' gestation
Our community guideline provides an evidence based risk assessment, a list of factors suitable for early referral, and a two tiered schedule of assessment and step-up referral for signs and symptoms of pre-eclampsia
This is a practical extension of NICE's antenatal guideline
Wednesday, March 09, 2005
Nikolai Sergeievichj Korotkov (www.whonamedit.com)
Nikolai Sergeievichj Korotkov (www.whonamedit.com)
In November 05, 1905 Korotkov presentd during a scientific meeting at the Military Hospital of the Imperial Military Academy a short communication : "Concerning the problem of the methods for investigating blood pressure"
In November 05, 1905 Korotkov presentd during a scientific meeting at the Military Hospital of the Imperial Military Academy a short communication : "Concerning the problem of the methods for investigating blood pressure"
laugh is good for the heart
A good laugh is good for the heart, according to a study by researchers at the University of Maryland School of Medicine.
Researchers presented their findings at the Scientific Session of the American College of Cardiology in Orlando, Florida.
For their findings, the team showed two movies to 20 healthy non-smoking, volunteers and tested the function of their blood vessels.
They found that laughter-provoking movies, such as "King Pin" increased blood flow by an average of 22 percent compared with a decrease of 35 percent for stressful movies such as "Saving Private Ryan."
The team reported laughter appears to cause the tissue that forms the inner lining of blood vessels called the endothelium, to dilate or expand in order to increase blood flow.
Researchers presented their findings at the Scientific Session of the American College of Cardiology in Orlando, Florida.
For their findings, the team showed two movies to 20 healthy non-smoking, volunteers and tested the function of their blood vessels.
They found that laughter-provoking movies, such as "King Pin" increased blood flow by an average of 22 percent compared with a decrease of 35 percent for stressful movies such as "Saving Private Ryan."
The team reported laughter appears to cause the tissue that forms the inner lining of blood vessels called the endothelium, to dilate or expand in order to increase blood flow.
Tuesday, March 08, 2005
STEM CELLS: Which ones and why?
(Referência do Reginaldo H. Albuquerque, do Cardiosource.)
The Challenge
Among survivors of myocardial infarction (MI), heart failure frequently ensues as a consequence of cell loss and scar formation in myocardium within the distribution area of the infarct-related artery. In theory, late revascularization might enable hibernating myocardium to recover contractility.1
Cell transplantation may be one means of achieving late myocardial recovery and restoration. Various delivery methods are being evaluated using a variety of cell types (Slide 1), including skeletal myoblasts, endothelial progenitor cells from peripheral blood, and hematopoietic or mesenchymal stem cells derived from fatty tissue or bone marrow.2
The Challenge
Among survivors of myocardial infarction (MI), heart failure frequently ensues as a consequence of cell loss and scar formation in myocardium within the distribution area of the infarct-related artery. In theory, late revascularization might enable hibernating myocardium to recover contractility.1
Cell transplantation may be one means of achieving late myocardial recovery and restoration. Various delivery methods are being evaluated using a variety of cell types (Slide 1), including skeletal myoblasts, endothelial progenitor cells from peripheral blood, and hematopoietic or mesenchymal stem cells derived from fatty tissue or bone marrow.2
Dia Internacional da Mulher
HOMENAGEM TAMBÉM A TODAS NOSSAS MULHERES AMICOR!....
Dia Internacional da Mulher: SIMERS rende homenagem à primeira médica do Brasil
Porto Alegre, 4 de fevereiro de 2005.
A Prefeitura de Rio Pardo e o Sindicato Médico do Rio Grande do Sul (SIMERS) vão reverenciar na terça-feira, dia 8, a memória de uma das mulheres pioneiras no Brasil. Para marcar o Dia Internacional da Mulher no Estado, o município, por meio do Arquivo Histórico e Câmara de Vereadores, e o SIMERS farão ato no Museu Municipal lembrando os feitos da gaúcha Rita Lobato, a primeira médica formada no Brasil. Rita, que morreu em 1954 aos 87 anos, rompeu a fronteira da Medicina e foi também a primeira vereadora eleita no país. Ela foi ainda a segunda médica formada na América Latina.
...........
Dia Internacional da Mulher: SIMERS rende homenagem à primeira médica do Brasil
Porto Alegre, 4 de fevereiro de 2005.
A Prefeitura de Rio Pardo e o Sindicato Médico do Rio Grande do Sul (SIMERS) vão reverenciar na terça-feira, dia 8, a memória de uma das mulheres pioneiras no Brasil. Para marcar o Dia Internacional da Mulher no Estado, o município, por meio do Arquivo Histórico e Câmara de Vereadores, e o SIMERS farão ato no Museu Municipal lembrando os feitos da gaúcha Rita Lobato, a primeira médica formada no Brasil. Rita, que morreu em 1954 aos 87 anos, rompeu a fronteira da Medicina e foi também a primeira vereadora eleita no país. Ela foi ainda a segunda médica formada na América Latina.
...........
Monday, March 07, 2005
Thursday, March 03, 2005
[2236 - AMICOR - 03/Março/2005] AMICOR; AMICOR SMOKE; AMICOR PRESERVE
Caros AMICOR,
A menor frequência das mensagens de alerta se devem às férias e às reformulações no estilo da comunicação AMICOR. Novas referências estarão sendo acrescentadas na medida em que forem sendo encontradas. Assim quando tiverem oportunidade, podem visitar os endereços de seu interesse, independentemente de mensagem de alerta.
Dear AMICOR,
Our alert messages are now less frequent due to the vacation period and to the addaptation to the new AMICOR style. New references will be added as they will be found. So, when you have an opportunity you are invited to visit the addresses of you interest, independently of the alert message.
http://amicor.blogspot.com
Neurohumoral Features of Myocardial Stunning Due to Sudden Emotional Stress
Minding the gender gap: The divergence between men's and women's health research
Plaque Instability Frequently Occurs Days or Weeks Before Occlusive Coronary Thrombosis
Lack of women cardiologists might lower standards -- Dobson 330 (7488): 379 -- BMJ
COX-2 Inhibitors — Lessons in Drug Safety
Association of weight change with ethnicity and life course socioeconomic position among Brazilian civil servants
http://amicorsmoke.blogspot.comAusência Previsível
Fumicultores querem garantias do governo; indústria ataca tratado
El Convenio Marco para el Control del Tabaco entra en vigor
http://amicor_preserve.blogspot.com
A nova Philips Gigante holandesa de eletrônicos agora mira em hospitais e clnicas e transformasetor de saúde na prioridade mundial
Amartya Sen and the capability approach
A menor frequência das mensagens de alerta se devem às férias e às reformulações no estilo da comunicação AMICOR. Novas referências estarão sendo acrescentadas na medida em que forem sendo encontradas. Assim quando tiverem oportunidade, podem visitar os endereços de seu interesse, independentemente de mensagem de alerta.
Dear AMICOR,
Our alert messages are now less frequent due to the vacation period and to the addaptation to the new AMICOR style. New references will be added as they will be found. So, when you have an opportunity you are invited to visit the addresses of you interest, independently of the alert message.
http://amicor.blogspot.com
Neurohumoral Features of Myocardial Stunning Due to Sudden Emotional Stress
Minding the gender gap: The divergence between men's and women's health research
Plaque Instability Frequently Occurs Days or Weeks Before Occlusive Coronary Thrombosis
Lack of women cardiologists might lower standards -- Dobson 330 (7488): 379 -- BMJ
COX-2 Inhibitors — Lessons in Drug Safety
Association of weight change with ethnicity and life course socioeconomic position among Brazilian civil servants
http://amicorsmoke.blogspot.comAusência Previsível
Fumicultores querem garantias do governo; indústria ataca tratado
El Convenio Marco para el Control del Tabaco entra en vigor
http://amicor_preserve.blogspot.com
A nova Philips Gigante holandesa de eletrônicos agora mira em hospitais e clnicas e transformasetor de saúde na prioridade mundial
Amartya Sen and the capability approach
Neurohumoral Features of Myocardial Stunning Due to Sudden Emotional Stress
Neurohumoral Features of Myocardial Stunning Due to Sudden Emotional Stress
artigo científico discutido hoje no serviço de cardiologia do HMV.
Apresentador: Luis Beck SIlva Neto.
Ilan S. Wittstein, et al.
Conclusions Emotional stress can precipitate severe, reversible left ventricular dysfunction in patients without coronary disease. Exaggerated sympathetic stimulation is probably central to the cause of this syndrome.
artigo científico discutido hoje no serviço de cardiologia do HMV.
Apresentador: Luis Beck SIlva Neto.
Ilan S. Wittstein, et al.
Conclusions Emotional stress can precipitate severe, reversible left ventricular dysfunction in patients without coronary disease. Exaggerated sympathetic stimulation is probably central to the cause of this syndrome.
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