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Monday, June 27, 2022

3.091 AMICOR (25)

 3.091 - AMICOR (25) 

Agradeço a todos que já se manifestaram sobre continuidade e conteúdo de nosso Blog, e me mantenho atento para qualquer sugestão adicional. Segue o convite inicial:

Como sabem, já fazem 25 anos que estou na rede, tentando me manter atualizado. A proposta inicial era de um instrumento para guardar referências interessantes, disponibilizando-as também para amigos e visitantes...Com o desenvolvimento dos meios de comunicação, sempre me questiono da sua utilidade, e de como me manter atualizado. Opiniões, críticas e sugestões serão sempre bem vindas.

#Dra. Valderês Antonietta Robinson Achutti (*13/06/1931+15/06/2021) 

Dentro das muralhas do Kremlin em junho de 1985 
Durante 1o. Congresso Mundial de Cardiologia Preventiva

Dia 27/06/2022 Da. Lea Pizani Robinson estaria completando 111 anos. Para lembrá-la, acrescento uma foto dela com a primeira filha, Valderês, provavelmente de 1934.

Léa Pizani Robinson *27/06/1911 +25/06/1991 e Valderês *1931 + 2021


#Associação Amigos do Teatro São Pedro

Parabéns
ao Theatro São Pedro na semana de comemorações dos seus 164 anos. Vida longa a este ícone cultural da cidade, que não para de crescer, oferecendo cada vez mais opções de espaços e uma programação artística de alta qualidade. A Associação dos Amigos do Theatro São Pedro colabora nestas melhorias, e por isto, é fundamental a sua participação.
ASSOCIE-SE - Seja um amigo do Theatro São Pedro.

#LiveScience






















Doctors diagnosing monkeypox should be on the lookout for symptoms that don't quite match the typical descriptions of the disease, the Centers for Disease Control and Prevention (CDC) warned June 14.

Historically, monkeypox rashes tend to erupt around the face and in the oral cavity, first, and then may progress to the extremities, including the palms of the hands and soles of the feet. However, some of the recent monkeypox cases in the U.S. have diverged from this pattern, the CDC reported.
 Full Story: Live Science (6/28) 
#MUHM
#OSPA
Nosso neto, Antônio Achutti Olivé, particicpando de concerto no dia 27/06
No próximo dia 08/07 estarão se apresentando  em Buenos Aires no Teatro Colón

#Vera Elisabeth Veríssimo
(*15/02/1934 +30/06/2022)
Acabo de receber a triste notícia do falecimento de Vera Elisabeth Veríssimo, viúva de Franklin Veríssimo, um dos fundadores de nossa Academia Sul-Riograndense de Medicina, e autora da biografia dele.
Dentre suas prendas posso alinhar: Poeta (com vários livros publicados), Psicóloga, Professora de Inglês, e fez parte do Coral da AMRIGS, onde encontrou Dra. Valderês Antonietta Robinson Achutti.

#SBC

ABC Cardiol alcança maior fator de impacto de sua história
Com este marco, a publicação se consolida como a melhor revista científica de cardiologia na América Latina.

Leia na íntegra







#Universidade LaSalle
#CHC Santa Casa
#
My Bookmarks

CONDENSED MATTER PHYSICS | ALL TOPICS

 

Controversy Continues Over Whether Hot Water Freezes Faster Than Cold

By ADAM MANN

Decades after a Tanzanian teenager initiated study of the “Mpemba effect,” the effort to confirm or refute it is leading physicists toward new theories about how substances relax to equilibrium.

Read the article

GEOLOGY

 

Life Helps Make Almost Half of All Minerals

By JOANNA THOMPSON

A new system for classifying minerals reveals the huge geochemical imprint of biology on Earth and could help us identify other worlds with life too.

Read the blog

Related: 
How Life and Luck
Changed Earth’s Minerals

by Roberta Kwok (2015)

THE JOY OF WHY

 

Can Computers Be Mathematicians?

Podcast hosted by STEVEN STROGATZ

A global, multidisciplinary effort is underway to write the essential axioms of math in a language that AI can understand. Hear Steven Strogatz interview Kevin Buzzard, one of the project’s key contributors, on the latest episode of The Joy of Why.

Listen to the podcast

Read the transcript

AGING

 

Protein Blobs Linked to Alzheimer’s Affect Aging in All Cells

By VIVIANE CALLIER

Protein buildups like those seen around neurons in Alzheimer’s, Parkinson’s and other brain diseases occur in all aging cells, a new study suggests. Learning their significance may reveal new strategies for treating age-related diseases.

Read the article

QUANTIZED COLUMNS

 

The Sordid Past of the Cubic Formula

By DAVID S. RICHESON

Almost 500 years ago, reputations were ruined and vows were broken over how to solve cubic equations. Learn more about this historic betrayal.

Read the column

Related: 
Mathematicians Resurrect
Hilbert’s 13th Problem

by Stephen Ornes (2021)

INSIGHTS PUZZLE

 

How to Weigh Truth With a Balance Scale

By PRADEEP MUTALIK

In recreational mathematics, the balance scale is an endless source of puzzles that require precise logic and teach the fundamentals of generalization.

Solve the puzzle

Around the Web

A Moment of Crystalline Perfection
A time crystal is a phase of matter that emulates the periodic structure of a regular crystal, but instead of repeating a pattern in space, it repeats it in time. Dianna Cowern explains time crystals for her YouTube channel The Physics Girl. Time crystals were first theorized in 2013, then experimentally realized on Google’s quantum computer last year. Natalie Wolchover wrote about the experiment for Quanta.


Where Do You Get That Glow?
Bioluminescent bacteria can make the ocean glow. Sailors have noticed it for centuries, but now some are joining forces with scientists to study the science behind this “milky sea,” writes Sam Keck Scott for Hakai Magazine. Although bioluminescence is relatively common in nature, it’s poorly understood. In 2016 Steph Yin wrote for Quanta about studies that had started to reveal the evolutionary and chemical origins of the phenomenon.

Sunday, June 19, 2022

3.090 - AMICOR (25)

  3.090 - AMICOR (25) 

Caríssimos AMICOR, como sabem já fazem 25 anos que estou na rede, já andei fazendo várias mudanças e adaptações, mas cada vez mais me questiono se devo manter esta atividade e, no caso, o que e como me atualizar. Também foi minha proposta desde o início ter um instrumento para guardar o que me interessa, disponibilizando-o para meus amigos, ou a quem mais possa interessar...

Para encontrar com mais tranquilidade meu caminho daqui por diante, seria de muita valia se pudesse contar com a opinião, crítica e sugestões de quem tem me visitado, ainda mais porque não conto mais com o conselho de quem me ajudou durante setenta anos.

Muito obrigado, Aloyzio.

#Dra. Valderês Antonietta Robinson Achutti (*13/06/1931+15/06/2021

Aproveitando a celebração do dia do Pai (19/06): Não lembro onde nem quando , mas tenho saudade do calorzinho dela...
                                        (clicar  em Apresentação de Slides)

#CENTRO LATINO-AMERICANO PARA PROMOÇÃO DA SAÚDE CARDIOVASCULAR - Parceria Medscape & ACC

Recomendado pela AMICOR Maria Inês Reinert Azambuja

#MEDSCAPE

Ryan Syrek

NOTIFICAÇÃO 

17 de junho de 2022 

Um dos medicamentos geralmente mais prescritos no mundo, a metformina, é usado primariamente para tratar o diabetes mellitus tipo 2. Novas pesquisas sobre seus potenciais efeitos benéficos para tratar outras doenças, bem como questões emergentes sobre seus efeitos adversos, fizeram com que este medicamento se tornasse o tema clínico mais buscado da semana. Talvez mais especificamente, os resultados recém-divulgados de um ensaio clínico marcante tenham sido muito decepcionantes/.../
#Nature briefing

#ASRM
#
My Bookmarks

MACHINE LEARNING | ALL TOPICS

 

By Exploring Virtual Worlds, AI Learns in New Ways

By ALLISON WHITTEN

Intelligent beings learn by interacting with the world. Artificial intelligence researchers have adopted a similar strategy to teach their virtual agents new skills.

Read the article

EXPLAINERS

 

The Spooky Quantum Phenomenon You’ve Never Heard Of

By KATIE McCORMICK

Contextuality isn’t as famous as nonlocality, but researchers think it may be what gives quantum computers an advantage over their classical cousins.

Read the blog


Related: 
How Bell’s Theorem Proved
‘Spooky Action at a Distance’ Is Real

by Ben Brubaker (2021)

Q&A

 

An Immunologist Fights Covid with Tweets and a Nasal Spray

By YASEMIN SAPLAKOGLU

On Twitter, immunologists like Akiko Iwasaki are educating the public in real time about developments in the pandemic, including the potential of nasal spray vaccines.

Read the interview


Related: 
‘Trained Immunity’ Offers Hope
in Fight Against Coronavirus

by Esther Landhuis (2020)

GRAPH THEORY

 

Mathematical Connect-the-Dots Reveals How Structure Emerges

By LEILA SLOMAN

A new proof identifies precisely how large a mathematical graph must be before it contains a regular substructure.

Read the blog


Related: 
Surfaces Beyond Imagination Are
Discovered After Decades-Long Search

by Leila Sloman

QUANTA SCIENCE PODCAST

 

This Animal’s Behavior Is Mechanically Programmed

Podcast hosted by SUSAN VALOT;
Story by JORDANA CEPELEWICZ

Biomechanical interactions, rather than neurons, control the movements of one of the simplest animals. The discovery offers a glimpse into how animal behavior worked before neurons evolved.

Listen to the podcast

Read the article

Around the Web

When Viruses Get Worse
Viruses often get milder over time, but that’s far from always the case. For The New York Times, Carl Zimmer considers the deadliest vertebrate virus, myxoma, which in the 1990s evolved to become more virulent among the rabbit populations it ravaged. The uncertainty of virus evolution is relevant to the COVID-19 pandemic. Virologists are trying to better understand this by mapping out the “fitness landscape” of all possible mutations of SARS-CoV-2, Carrie Arnold reported for Quanta in January.

Physicists Spot Strong Signs
Physicists think they have seen the first convincing evidence for the “tetraneutron,” a short-lived particle composed of four neutrons, Emily Conover reports for Science News. Studying this exotic particle could help us learn more about nuclear forces. The strong force binds neutrons together but also keeps individual neutrons together — until the weak force eventually wins and the neutron decays. In 2018 Natalie Wolchover wrote for Quanta about what we can learn from studying neutron lifetimes.
Follow Quanta


#The Marginalian - Maria Popova

The dandelion and the meaning of life, 20 reasons for being, poet Elizabeth Alexander on how literature widens the portal of the possible

The Dandelion and the Meaning of Life: G.K. Chesterton on How to Dig for the “Submerged Sunrise of Wonder”

There is a myth we live with, the myth of finding the meaning of life — as if meaning were an undiscovered law of physics. But unlike the laws of physics — which predate us and will postdate us and made us — meaning only exists in this brief interlude of consciousness between chaos and chaos, the interlude we call life. When you die — when these organized atoms that shimmer with fascination and feeling — disband into disorder to become unfeeling stardust once more, everything that filled your particular mind and its rosary of days with meaning will be gone too. From its particular vantage point, there will be no more meaning, for the point itself will have dissolved — there will only be other humans left, making meaning of their own lives, including any meaning they might make of the residue of yours./.../

#WHO

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Mental health is critically important to everyone, everywhere. All over the world, mental health needs are high but responses are insufficient and inadequate. This “World Mental Health Report” is designed to inspire and inform better mental health for all. It highlights why and where change is needed and how it can be achieved.

 

#AEON Magazine

In the jungle of Suriname, Maria Sibylla Merian discovered insect metamorphosis

Borrowing from the elegant visual style of the German-born Swiss naturalist, entomologist and botanical artist Maria Sibylla Merian (1647-1717), this animation celebrates her many notable contributions to the natural sciences in an age when such work was widely considered the domain of men. A dedicated observer of plants and insects in particular, two of her many achievements include helping to dispel the once widely held belief that insects spontaneously emerge from dust, mud or rotten meat, and observing metamorphosis in rich detail. And 300 years after her death, her seminal book, The Metamorphosis of the Insects of Suriname (1705), which depicts insects and plants in the jungles of South America, is still considered one of the most beautiful and groundbreaking entomology books ever assembled, with editions of the pioneering work being reprinted as recently as 2010. Video by The Royal Society and BBC Ideas Animation: Studio Panda 30 May 2022

#JAMA

US Preventive Services Task Force 
Evidence Report
June 21, 2022

Vitamin and Mineral Supplements for the Primary Prevention of Cardiovascular Disease and CancerUpdated Evidence Report and Systematic Review for the US Preventive Services Task Force

JAMA. 2022;327(23):2334-2347. doi:10.1001/jama.2021.15650
Conclusions and Relevance  Vitamin and mineral supplementation was associated with little or no benefit in preventing cancer, cardiovascular disease, and death, with the exception of a small benefit for cancer incidence with multivitamin use. Beta carotene was associated with an increased risk of lung cancer and other harmful outcomes in persons at high risk of lung cancer././
#JAMA
June 21, 2022

New Test to Help Diagnose Alzheimer Disease

JAMA. 2022;327(23):2281. doi:10.1001/jama.2022.9847

The FDA recently permitted Fujirebio Diagnostics to market the first in vitro diagnostic biomarker test for early detection of amyloid plaques associated with Alzheimer disease.

The Lumipulse G β-Amyloid Ratio (1-42/1-40) test could potentially eliminate the need for positron emission tomography (PET) scans to assess amyloid plaques in patients’ brains, Jeff Shuren, MD, JD, director of the FDA’s Center for Devices and Radiological Health, said in a statement.

To expedite development and review, the agency had designated the Lumipulse test as a breakthrough device, a classification reserved for devices that might more effectively treat or diagnose life-threatening or irreversibly debilitating diseases or conditions.

The new test is intended for use among patients aged 55 years or older to help determine whether their cognitive impairment is due to Alzheimer disease. It is designed to measure the ratio of β-amyloid 1-42 and β-amyloid 1-40 concentrations in cerebrospinal fluid (CSF), which can help determine the likelihood of amyloid plaques in the brain.

The Lumipulse test isn’t intended to be used as a screening or stand-alone diagnostic assay because patients with other neurological conditions, as well as older cognitively healthy people, could receive a positive result. The assay should be used only in conjunction with other clinical evaluations, according to the FDA.

The agency evaluated the test’s safety and effectiveness based on the results of a clinical study that compared results from 292 CSF samples with PET scan findings. Of the samples that had positive results on the Lumipulse test, 97% came from patients whose PET scans revealed the presence of amyloid plaques. Of the samples that had negative results on the Lumipulse test, 84% also had a negative amyloid PET scan.

#IHME


Global Dementia Care Spending and Future Spending Scenarios 2000-2050

This dataset contains retrospective estimates for healthcare spending attributable to dementia for 195 countries from 2000 to 2019 and prospective spending estimates from 2020 to 2050 under multiple scenarios. Intermediate and final estimates are provided. Intermediate estimates include community based care rate (CBC), nursing home based care rate (NHBC), community based care unit cost, and nursing home based care unit cost. Final estimates are attributable dementia spending. All spending is reported in 2019 United States dollars. Future estimates report the same model outputs as those reported in the retrospective model but include both reference and alternative scenarios based on accelerated care setting rates and units costs.
Publication year 
2022
Suggested citation 
Institute for Health Metrics and Evaluation (IHME). Global Dementia Care Spending and Future Spending Scenarios 2000-2050. Seattle, United States of America: Institute for Health Metrics and Evaluation (IHME), 2022.
DOI 
https://doi.org/10.6069/YZHV-H840
Terms and conditions

Data made available for download on IHME Websites can be used, shared, modified or built upon by non-commercial users in accordance with the IHME FREE-OF-CHARGE NON-COMMERCIAL USER AGREEMENT. For more information (and inquiries about commercial use), visit IHME Terms and Conditions.

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#Research Gate                                                                          

Rethinking the vaccine landscape

In this whitepaper, learn from Dr. Sanjay Garg, Senior Expert Scientist, Sanofi Pasteur about the direction of vaccine development, potential hurdles researchers and manufacturers might face, and how lessons learnt from COVID-19 will shape the future of vaccine development.
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www.perkinelmer.com
Rethinking the vaccine landscape