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Thursday, July 07, 2011

Sudden Cardiac Death Gene Trigger

Sudden Cardiac Death Gene Trigger Found

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By Chris Kaiser, Cardiology Editor, MedPage Today
Published: July 06, 2011
Reviewed by Dori F. Zaleznik, MD; Associate Clinical Professor of Medicine, Harvard Medical School, Boston and Dorothy Caputo, MA, RN, BC-ADM, CDE, Nurse Planner
For the first time in a community setting, researchers have identified a genomic hot spot that doubles the risk of sudden cardiac arrest.
The meta-analysis of five genome-wide association studies, which included 1,283 sudden cardiac death cases and more than 20,000 controls, led researchers to the BAZ2B locus, Dan E. Arking, PhD, from Johns Hopkins University School of Medicine in Baltimore, and colleagues reported.
The BAZ2B area contains three genes not previously known to play a role in cardiac biology, according to the study published online in PLoS Genetics./.../

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