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Sunday, June 16, 2013

Rapamicin

Lifespan-extending drug given late in life reverses age-related heart disease in mice

June 12, 2013
Lightmatter_lab_mice
Laboratory mice (credit: Lightmatter/Wikimedia Commons)
Elderly mice suffering from age-related heart disease saw a significant improvement in cardiac function after being treated with the FDA-approved drug rapamycin for just three months.
The research, led by a team of scientists at the Buck Institute for Research on Agingshows how rapamycin impacts mammalian tissues, providing functional insights and possible benefits for a drug that has been shown to extend the lifespan of mice as much as 14 percent.
There are implications for human health in the research appearing in Aging Cell. Heart disease is the leading cause of death in the U.S., claiming nearly 600,000 lives per year./.../

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