Periodontal Disease and Vascular Disease

Periodontal Disease and Atherosclerotic Vascular Disease:


/.../Evidence for PD as a Risk Factor for ASVD
The potential associations between PD and ASVD can be considered in light of published standards for levels of evidence that include Level of Evidence A, for which supportive data are derived from multiple randomized clinical trials or meta-analyses, and Level of Evidence B, for which data derive from a single randomized trial or nonrandomized studies. An association between PD and ASVD is supported by evidence that meets standards for Level of Evidence A. A benefit of periodontal intervention in decreasing local periodontal inflammation is also supported by level A evidence. Causation of ASVD by PD is not supported by either level A or level B evidence. The same is true about a benefit of periodontal intervention in decreasing longterm systemic inflammation./.../