Prostate Cancer
*Prostate Cancer Updates* *From Medscape Urology* Cancer Deaths Falling, but Uptick in Late-Stage Prostate Cancer 'Historic Reversal': No Immediate Tx for Low-Risk Prostate Cancer MEAL: Men Changed Diet but Not Prostate Cancer Progression French Twist: ADT for Prostate Cancer on Active Surveillance 'Notable Differences' With 3 Prostate Cancer Genomics Tests New Data: Finasteride Safely Prevents Prostate Cancer ASCO Issues New Metastatic Prostate Cancer Treatment Guide *Editor's Note * From record numbers of men opting for "watchful waiting" for low-risk prostate cancer, to advances... mais »
Hypertension Guidelines
Association of the 2014 and 2017 Hypertension Guidelines With Cardiovascular Events and Deaths in US Adults JAMA Cardiology This study estimates the potential association of the 2017 and 2014 hypertension guideline treatment goals with the proportion of US adults defined as being hypertensive or recommended for antihypertensive treatment. The New Hypertension Guidelines (Editor's Note)
Alzheimer
Interactive Associations of Vascular Risk and β-Amyloid Burden With Cognitive Decline in Clinically Normal People JAMA Neurology This longitudinal study assesses whether vascular risk and β-amyloid burden act additively or synergistically to promote cognitive decline in clinically normal older adults.
Roundup
Processo legal afirma que a Monsanto sabia do perigo carcinogênico do seu herbicida, e o negou de propósito por décadas Posted: 26 May 2018 04:00 AM PDT Em processo iniciado por um americano com linfoma terminal, a Monsanto está sendo acusada de ter conhecimento e ativamente esconder os perigos cancerígenos de seus populares produtos herbicidas Roundup por décadas
consumer genetic testing
The story worth a long read Grab yourself a cup of coffee, sit down and read the *first part of Tina Hesman Saey's sprawling series on consumer genetic testing*. It's an epic journey. Maybe you've seen the ads for consumer genetic tests offered by 23andMe or AncestryDNA. Maybe you're one of the millions that have tried the tests for yourself. Well, Tina tried eight. And with a Ph.D. in genetics, she knows a thing or two about understanding the results. Let's just say these companies promise more than they can deliver. Make sure to check out her *detailed review of 23andMe, Veritas Ge... mais »
Universe and Hawking
Singularity: Poet Marie Howe’s Beautiful Tribute to Stephen Hawking and Our Belonging to the Universe When *Stephen Hawking* (January 8, 1942–March 14, 2018) was a young man, having already outlived the prognosis he had been given with ALS, he built on earlier theories about what happens to a dying star as it collapses to form a singularity — that tiny point of zero radius, infinite density, and infinite curvature of spacetime at the heart of a black hole. But then Hawking did something radical — he took this final death-stage and flipped the arrow of time to consider what would happ... mais »
Ha 50 anos transplante de coração
Há 50 anos, o primeiro transplante de coração no BrasilNa madrugada de 26 de maio de 1968, equipe liderada pelo médico Euryclides de Jesus Zerbini fez no HC/USP o primeiro procedimento do tipo na América Latina Por *Letícia Passos* access_time25 maio 2018, 14h42 - Publicado em 25 maio 2018, 06h00 Equipe que atuou no primeiro transplante cardíaco - 1968 (Museu FMUSP/Arquivo) Na madrugada de 26 de maio de 1968, Euryclides de Jesus Zerbini, cirurgião do Hospital das Clínicas da Universidade de São Paulo (HC-USP), revolucionou a medicina ao liderar a equipe que realizou o primeiro *t... mais »
No dia 11 p.p. apresentei neste Blog AMICOR um artigo assinado por mim e pelo Professor *Eduardo de Azeredo Costa* referente à uma história de 40 anos atrás, lembrando a Pesquisa sobre Pressão Arterial realizada no Rio Grande do Sul em amostra representativa da população adulta (de 20 a 74 anos) de todo o Estado. Teve início no mês de maio de 1978, em seguimento a um programa do ano anterior da Secretaria da Saúde e do Meio Ambiente, de prevenção da Doença Hipertensiva na comunidade. Foi um marco no início da incorporação da Hipertensão na agenda de Saúde Pública, seguindo-se a mobi... mais »
Chronic Pain
Frontal Lobe Implicated in Chronic Painby Neuroscience News A new study reveals, in rodents, some spinal pain begins in the frontal cortex. Researchers say the findings could help in the development of new treatments for chronic pain. Read more of this post *Neuroscience News* | May 26, 2018 at 9:35 am | Tags: computer science, inflammtion, RVM, University of Toronto | URL: https://wp.me/p4sXNK-cLs Comment See all comments
Rules of Life
NSF-Simons centers to search for the Rules of Life New, $10 million centers bridge biology and mathematics to uncover how genetic codes spawn complex life [image: close up of fruit fly eye] As a fruit fly’s eye develops, structural complexity emerges. - Credit and Larger Version - May 24, 2018 The National Science Foundation (NSF), in partnership with the Simons Foundation, has launched four new centers to bring mathematical perspectives to the biological search for the Rules of Life. The National Science Foundation (NSF), in partnership with the Simons Foundation, has launche... mais »
Metrópoles Oservatório Biblioteca
Nova Biblioteca Digital Observatório Metrópoles 100 livros para download Em mais uma ação comemorativa dos seus 20 anos de história (1998-2018), o INCT Observatório das Metrópoles promove o lançamento sua nova Biblioteca Digital com o objetivo de dar continuidade à sua política de difusão científica com o compartilhamento amplo e gratuito de toda a sua produção de conhecimento. As publicações fazem parte da trajetória da rede de pesquisa e o seu compromisso com o desenvolvimento metropolitano brasileiro, especialmente os resultados do período 2009-2018 no qual o Observatório passou ... mais »
Hipertansão Arterial: Tratamento
*Hipertensão arterial: que medicação iniciar primeiro?* Foi recentemente publicada pela *Cochrane Library* uma revisão sistemática sobre o início de tratamento em pacientes com hipertensão moderada a grave. Solidas evidências indicam que diuréticos tiazídicos em baixa dose reduzem morbidade e mortalidade e podem ser considerados os primeiros agentes utilizados na maioria dos adultos com hipertensão arterial primária. Inibidores da ECA e bloqueadores dos canais podem ter eficácia similar, mas o nível de evidência é inferior. Leia mais sobre o estudo: http://cochranelibrary-wiley.c... mais »
Managing Neuropsychiatric Symptoms
*The Latest in * *Clinical & Translational Medicine* Featured Event *Managing Neuropsychiatric Symptoms in Neurodegenerative Disease*June 14, 2018 This symposium will review current methods in the diagnosis and behavioral and pharmaceutical management of neuropsychiatric symptoms in neurodegenerative diseases. Participants will also discuss strategies to reduce the societal and economic costs associated with these symptoms. *This event will also be available via Webinar - register today.* *Featured Speaker:* Jeff Cummings, MD, ScD Cleveland Clinic Lou Ruvo Center for Brain Health
Memory Biology
Memory Molecule Limits Plasticity by Calibrating Calciumby Neuroscience News Researchers have identified a novel role the RGS14 protein plays in limiting synaptic plasticity. Read more of this post *Neuroscience News* | May 23, 2018 at 11:02 am | Tags: long-term potentiation, RGS14 | URL: https://wp.me/p4sXNK-cK2 Comment See all comments http://neurosciencenews.com/plasticity-calcium-memory-9121/ [image: neuron]Signaling diagram of a CA2 dendritic spine from a RGS14 KO mouse depicting mechanistic targets of the pharmacological inhibitors of Ca2+-dependent signaling pathways investig... mais »
0.01% destroyed 83%
Humans just 0.01% of all life but have destroyed 83% of wild mammals – study Groundbreaking assessment of all life on Earth reveals humanity’s surprisingly tiny part in it as well as our disproportionate impact Damian CarringtonEnvironment editor @dpcarrington Mon 21 May 2018 20.00 BSTLast modified on Tue 22 May 2018 15.10 BST - - - Shares 118,044 Comments2,295 [image: Cattle farm at Estancia Bahia, Agua Boa, Mato Grosso, Brazil] A cattle farm in Mato Grosso, Brazil. 60% of all mammals on Earth are livestock. Photograph: Daniel Beltra/Greenpeace Humankind is revealed as si... mais »
Nipah virus
What is the Nipah virus? The Nipah virus is a highly contagious and deadly virus that was first identified in 1999 when pig farmers in Malaysia and Singapore became very sick. During that outbreak, nearly 300 people were infected, and more than 100 people died. To stop the outbreak, authorities had to euthanize over one million pigs. Since then, the virus has been identified in outbreaks in Bangladesh and India. TheU.S. Centers for Disease Control and Prevention (CDC) says that outbreaks of Nipah virus now occur in Bangladesh almost every year, and there have been several outbreaks i... mais »
Geography matters
*Indicação da AMICOR Maria Inês Reinert Azambuja*The Rich Live Longer Everywhere.For the Poor, Geography Matters. By NEIL IRWIN and QUOCTRUNG BUI APRIL 11, 2016 For poor Americans, the place they call home can be a matter of life or death. The poor in some cities — big ones like New York and Los Angeles, and also quite a few smaller ones like Birmingham, Ala. — live nearly as long as their middle-class neighbors or have seen rising life expectancy in the 21st century. But in some other parts of the country, adults with the lowest incomes die on average as young as people in much poo... mais »
Health Inequality
[image: Image description not available.] Income, Poverty, and Health Inequality Dave A. Chokshi, MD, MSc1 Author Affiliations Article Information JAMA. 2018;319(13):1312-1313. doi:10.1001/jama.2018.2521 The health of people with low incomes historically has been a driver of public health advances in the United States. For example, in New York City, cholera deaths during outbreaks in 1832 and 1854 concentrated among the poor helped push forward the Metropolitan Health Law, which allowed for regulation of sanitary conditions in the city. The law was an exemplar for other municipalities ... mais »
Stephen Hawking: 3 Publications
[image: Stephen Hawking: 3 Publications That Shaped His Career] ARTS & CULTURE Stephen Hawking: 3 Publications That Shaped His Career
Five Books
By LUCY FELDMAN 11:06 AM EDT Bill Gates wants you to do some serious thinking this summer. For his annual list of the best books to read this season, Gates has selected five heavy hitters that pose big questions:* “What makes a genius tick? Why do bad things happen to good people? Where does humanity come from, and where are we headed?”* But beach readers need not worry. In a post announcing his picks on Gates Notes, he adds: “All these books are fun to read, and most of them are pretty short.” Here, the five books Gates wants you to read this summer./.../
Design natural
A lei da física que controla discretamente sua vida - e pode ajudar a melhorá-la - 20 maio 2018 - mpartilhe este post com Facebook - Compartilhe este post com Twitter - Compartilhe este post com Messenger - Compartilhe este post com Email - [image: Cânion nos EUA]Direito de imagemGETTY IMAGESImage captionCom sua teoria Constructal, Bejan diz poder explicar 'a evolução de tudo' Por que um cacto tem a forma ideal para viver em um habitat sem água? Por que muitos rios formam curvas ao avançar rumo à sua foz? Há uma teoria da física que explica isso. Na ver... mais »
schizophrenia cell types
Cell Types Underlying Schizophrenia Identifiedby Neuroscience News Researchers have identified different neuron types and provided a new list of genes associated with schizophrenia. The findings could pave the way for developing new targeted therapies to treat the condition. Read more of this post *Neuroscience News* | May 21, 2018 at 10:32 am | Tags: medium spiny neurons , MSNs | URL: https://wp.me/p4sXNK-cIA Comment See all comments
Commune de Paris
*1871:* [image: Adolphe Thiers]The Commune of Paris revolted against the French national government under Adolphe Thiers , beginning a period of violence known as “Bloody Week.”
Microbiome and Atherosclerosis
New Online Views 15,419 Citations 0 61 Viewpoint May 14, 2018 The Microbiome and Risk for Atherosclerosis Anthony L. Komaroff, MD1 Author Affiliations Article Information JAMA. Published online May 14, 2018. doi:10.1001/jama.2018.5240 Hot new areas of biomedicine sometimes generate cool skepticism. Little more than a decade ago, investigators proposed that the gut microbiome might be contributing to obesity. Since then, the microbiome has been linked to numerous major diseases, including atherosclerosis, although some have been skeptical about this association. How could the gut... mais »
Two hundred years of blue
Two Hundred Years of BlueCerulean splendor from Goethe, Thoreau, Virginia Woolf, Vladimir Nabokov, Rachel Carson, Toni Morrison, and other literary masters.BY MARIA POPOVA With Carl Sagan’s poetic *Pale Blue Dot* on my mind lately, I have found myself dwelling on the color blue and the way our planet’s elemental hue, the most symphonic of the colors, recurs throughout our literature as something larger than a mere chromatic phenomenon — a symbol, a state of being, a foothold to the most lyrical and transcendent heights of the imagination. Gathered here is a posy of blue from some of ... mais »
World Social Mobility
*World Bank Pubs*Verified account @WBPubs 3m3 minutes ago More A new database that covers more than 95% of the global population offers a glimpse into economic mobility around the world http://wrld.bg/kwqw30k5b9c #FairProgress
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