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Study Authors: Jeanne Tie, Joshua D. Cohen, et al.; Harry B. Burke, Scott Kopetz
Target Audience and Goal Statement: Oncologists, gastroenterologists, pathologists, hematologists
The goal of this study was to examine if serial post-surgical and post-chemotherapy circulating tumor DNA (ctDNA) analysis could provide a real-time indication of adjuvant therapy efficacy in stage III colon cancer.
Question Addressed:
- Did a correlative biomarker study in patients with stage III colon cancer undergoing standard adjuvant chemotherapy demonstrate an association between post-surgical and post-chemotherapy ctDNA detection and risk of recurrence?/.../
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